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 UNC Health Pardee says it's the first health care organization in Western North Carolina to administer a newly FDA-approved drug to treat Alzheimer's disease.

The hospital says Dr. Joel Callahan, chief of staff with UNC Health Pardee, and medical director, Pardee Neurology Associates, administered the first dose of Lecanemab on Dec. 1, 2023, to an 81-year-old woman from Hendersonville.

According to UNC Health Pardee, the patient, who had a confirmed Alzheimer's disease diagnosis earlier this summer, said she was cautiously optimistic about the medication.

While we would rather have a proven remedy, we're doing the best we can with a horrible situation," the patient's husband said in a written statement.

The couple said they would have traveled anywhere to access this medication, so getting it in their community was a welcome benefit. They expressed they're hopeful for positive outcomes and glad to be a part of something that is a step toward a cure.

 The FDA fully approved Lecanemab in July 2023 for patients with early or mild memory issues related to Alzheimer's disease. According to the Mayo Clinic, Lecanemab works by reducing clumps of proteins called amyloid-beta proteins that play a key role in Alzheimer's. Reducing amyloid-beta proteins in the brain modestly slows memory and thinking decline from the disease.
"The approval of Lecanemab for the treatment of Alzheimer's is an exciting and important first step," Dr. Callahan said in a written statement. "Despite some of the risks, drawbacks, and limitations of this new treatment, the progress made after decades of failed advancement remains a reason for optimism in the treatment and, perhaps one day, cure of this disease."